Spontaneous dormancy of metastatic breast cancer cells in an all human liver microphysiologic system

BACKGROUND: Metastatic outgrowth in breast cancer can occur years after a seeming cure. Existing model systems of dormancy are limited as they do not recapitulate human metastatic dormancy without exogenous manipulations and are unable to query early events of micrometastases. METHODS: Here, we desc...

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Dettagli Bibliografici
Pubblicato in:Br J Cancer
Autori principali: Wheeler, S E, Clark, A M, Taylor, D P, Young, C L, Pillai, V C, Stolz, D B, Venkataramanan, R, Lauffenburger, D, Griffith, L, Wells, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
Soggetti:
Molecular Diagnostics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264444/
https://ncbi.nlm.nih.gov/pubmed/25314052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.533
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