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A liver microphysiological system of tumor cell dormancy and inflammatory responsiveness is affected by scaffold properties

Distant metastasis is the major cause of breast cancer-related mortality, commonly emerging clinically after 5 or more years of seeming ‘cure’ of the primary tumor, indicating a quiescent dormancy. The lack of relevant accessible model systems for metastasis that recreate this latent stage has hinde...

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Bibliographische Detailangaben
Veröffentlicht in:Lab Chip
Hauptverfasser: Clark, AM, Wheeler, SE, Young, CL, Stockdale, L, Shepard, Neiman J, Zhao, W, Stolz, DB, Venkataramanan, R, Lauffenburger, D, Griffith, L, Wells, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242229/
https://ncbi.nlm.nih.gov/pubmed/27910972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6lc01171c
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