Prevention of chemotherapy‐induced cachexia by ACVR2B ligand blocking has different effects on heart and skeletal muscle

BACKGROUND: Toxicity of chemotherapy on skeletal muscles and the heart may significantly contribute to cancer cachexia, mortality, and decreased quality of life. Doxorubicin (DOX) is an effective cytostatic agent, which unfortunately has toxic effects on many healthy tissues. Blocking of activin rec...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cachexia Sarcopenia Muscle
Egile Nagusiak: Hulmi, Juha J., Nissinen, Tuuli A., Räsänen, Markus, Degerman, Joni, Lautaoja, Juulia H., Hemanthakumar, Karthik Amudhala, Backman, Janne T., Ritvos, Olli, Silvennoinen, Mika, Kivelä, Riikka
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2017
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879968/
https://ncbi.nlm.nih.gov/pubmed/29230965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12265
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