Prevention of chemotherapy‐induced cachexia by ACVR2B ligand blocking has different effects on heart and skeletal muscle

BACKGROUND: Toxicity of chemotherapy on skeletal muscles and the heart may significantly contribute to cancer cachexia, mortality, and decreased quality of life. Doxorubicin (DOX) is an effective cytostatic agent, which unfortunately has toxic effects on many healthy tissues. Blocking of activin rec...

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Publicat a:J Cachexia Sarcopenia Muscle
Autors principals: Hulmi, Juha J., Nissinen, Tuuli A., Räsänen, Markus, Degerman, Joni, Lautaoja, Juulia H., Hemanthakumar, Karthik Amudhala, Backman, Janne T., Ritvos, Olli, Silvennoinen, Mika, Kivelä, Riikka
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879968/
https://ncbi.nlm.nih.gov/pubmed/29230965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12265
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