Immunogenicity of a Fap2 peptide mimotope of Fusobacterium nucleatum and its potential use in the diagnosis of colorectal cancer

BACKGROUND: The role of Fusobacterium nucleatum Fap2 protein in the development of colorectal cancer has recently been explained. Fap2, when bound to the human inhibitory receptor, TIGIT, inhibits the cytotoxic activity of natural killer (NK) cells against cancer cells, thus, allowing proliferation...

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Bibliografiska uppgifter
I publikationen:Infect Agent Cancer
Huvudupphovsmän: Guevarra, Leonardo A., Afable, Andrea Claudine F., Belza, Patricia Joyce O., Dy, Karen Joy S., Lee, Scott Justin Q., Sy-Ortin, Teresa T., Albano, Pia Marie S. P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2018
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879760/
https://ncbi.nlm.nih.gov/pubmed/29619076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13027-018-0184-7
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