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Immunogenicity of a Fap2 peptide mimotope of Fusobacterium nucleatum and its potential use in the diagnosis of colorectal cancer

BACKGROUND: The role of Fusobacterium nucleatum Fap2 protein in the development of colorectal cancer has recently been explained. Fap2, when bound to the human inhibitory receptor, TIGIT, inhibits the cytotoxic activity of natural killer (NK) cells against cancer cells, thus, allowing proliferation...

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Detalhes bibliográficos
Publicado no:Infect Agent Cancer
Main Authors: Guevarra, Leonardo A., Afable, Andrea Claudine F., Belza, Patricia Joyce O., Dy, Karen Joy S., Lee, Scott Justin Q., Sy-Ortin, Teresa T., Albano, Pia Marie S. P.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879760/
https://ncbi.nlm.nih.gov/pubmed/29619076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13027-018-0184-7
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