Immunogenicity of a Fap2 peptide mimotope of Fusobacterium nucleatum and its potential use in the diagnosis of colorectal cancer

BACKGROUND: The role of Fusobacterium nucleatum Fap2 protein in the development of colorectal cancer has recently been explained. Fap2, when bound to the human inhibitory receptor, TIGIT, inhibits the cytotoxic activity of natural killer (NK) cells against cancer cells, thus, allowing proliferation...

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Detaylı Bibliyografya
Yayımlandı:Infect Agent Cancer
Asıl Yazarlar: Guevarra, Leonardo A., Afable, Andrea Claudine F., Belza, Patricia Joyce O., Dy, Karen Joy S., Lee, Scott Justin Q., Sy-Ortin, Teresa T., Albano, Pia Marie S. P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879760/
https://ncbi.nlm.nih.gov/pubmed/29619076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13027-018-0184-7
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