Chronic stress promotes colitis by disturbing the gut microbiota and triggering immune system response

Chronic stress is known to promote inflammatory bowel disease (IBD), but the underlying mechanism remains largely unresolved. Here, we found chronic stress to sensitize mice to dextran sulfate sodium (DSS)-induced colitis; to increase the infiltration of B cells, neutrophils, and proinflammatory ly6...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Gao, Xinghua, Cao, Qiuhua, Cheng, Yan, Zhao, Dandan, Wang, Zhuo, Yang, Hongbao, Wu, Qijin, You, Linjun, Wang, Yue, Lin, Yanting, Li, Xianjing, Wang, Yun, Bian, Jin-Song, Sun, Dongdong, Kong, Lingyi, Birnbaumer, Lutz, Yang, Yong
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879702/
https://ncbi.nlm.nih.gov/pubmed/29531080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720696115
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