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Functional hierarchy underlies preferential connectivity disturbances in schizophrenia

Schizophrenia may involve an elevated excitation/inhibition (E/I) ratio in cortical microcircuits. It remains unknown how this regulatory disturbance maps onto neuroimaging findings. To address this issue, we implemented E/I perturbations within a neural model of large-scale functional connectivity,...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Yang, Genevieve J., Murray, John D., Wang, Xiao-Jing, Glahn, David C., Pearlson, Godfrey D., Repovs, Grega, Krystal, John H., Anticevic, Alan
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720350/
https://ncbi.nlm.nih.gov/pubmed/26699491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508436113
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