Chronic stress promotes colitis by disturbing the gut microbiota and triggering immune system response

Chronic stress is known to promote inflammatory bowel disease (IBD), but the underlying mechanism remains largely unresolved. Here, we found chronic stress to sensitize mice to dextran sulfate sodium (DSS)-induced colitis; to increase the infiltration of B cells, neutrophils, and proinflammatory ly6...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gao, Xinghua, Cao, Qiuhua, Cheng, Yan, Zhao, Dandan, Wang, Zhuo, Yang, Hongbao, Wu, Qijin, You, Linjun, Wang, Yue, Lin, Yanting, Li, Xianjing, Wang, Yun, Bian, Jin-Song, Sun, Dongdong, Kong, Lingyi, Birnbaumer, Lutz, Yang, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879702/
https://ncbi.nlm.nih.gov/pubmed/29531080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720696115
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