Uridine Adenosine Tetraphosphate-Induced Coronary Relaxation Is Blunted in Swine With Pressure Overload: A Role for Vasoconstrictor Prostanoids

Plasma levels of the vasoactive substance uridine adenosine tetraphosphate (Up(4)A) are elevated in hypertensive patients and Up(4)A-induced vascular contraction is exacerbated in various arteries isolated from hypertensive animals, suggesting a potential role of Up(4)A in development of hypertensio...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Zhou, Zhichao, Lankhuizen, Inge M., van Beusekom, Heleen M., Cheng, Caroline, Duncker, Dirk J., Merkus, Daphne
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879110/
https://ncbi.nlm.nih.gov/pubmed/29632487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00255
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