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Activation of adenosine A(2A) but not A(2B) receptors is involved in uridine adenosine tetraphosphate-induced porcine coronary smooth muscle relaxation

Activation of both adenosine A(2A) and A(2B) receptors (A(2B)R) contributes to coronary vasodilation. We previously demonstrated that uridine adenosine tetraphosphate (Up(4)A) is a novel vasodilator in the porcine coronary microcirculation, acting mainly on A(2A)R in smooth muscle cells (SMC). We fu...

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Detalhes bibliográficos
Publicado no:J Pharmacol Sci
Main Authors: Sun, Changyan, Jiao, Tong, Merkus, Daphne, Duncker, Dirk J., Mustafa, S. Jamal, Zhou, Zhichao
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7418061/
https://ncbi.nlm.nih.gov/pubmed/31640919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jphs.2019.09.006
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