The C3dg Fragment of Complement Is Superior to Conventional C3 as a Diagnostic Biomarker in Systemic Lupus Erythematosus

INTRODUCTION/OBJECTIVES: In 2012, hypocomplementemia was included in the classification criteria of systemic lupus erythematosus (SLE). The suggested measurement of C3 or C4 often reflect disease activity poorly. Our objective was to establish an assay measuring C3dg, which is generated following co...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Troldborg, Anne, Jensen, Lisbeth, Deleuran, Bent, Stengaard-Pedersen, Kristian, Thiel, Steffen, Jensenius, Jens Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879092/
https://ncbi.nlm.nih.gov/pubmed/29632534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00581
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