The C3dg Fragment of Complement Is Superior to Conventional C3 as a Diagnostic Biomarker in Systemic Lupus Erythematosus

INTRODUCTION/OBJECTIVES: In 2012, hypocomplementemia was included in the classification criteria of systemic lupus erythematosus (SLE). The suggested measurement of C3 or C4 often reflect disease activity poorly. Our objective was to establish an assay measuring C3dg, which is generated following co...

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Publicat a:Front Immunol
Autors principals: Troldborg, Anne, Jensen, Lisbeth, Deleuran, Bent, Stengaard-Pedersen, Kristian, Thiel, Steffen, Jensenius, Jens Christian
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879092/
https://ncbi.nlm.nih.gov/pubmed/29632534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00581
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