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The C3dg Fragment of Complement Is Superior to Conventional C3 as a Diagnostic Biomarker in Systemic Lupus Erythematosus

INTRODUCTION/OBJECTIVES: In 2012, hypocomplementemia was included in the classification criteria of systemic lupus erythematosus (SLE). The suggested measurement of C3 or C4 often reflect disease activity poorly. Our objective was to establish an assay measuring C3dg, which is generated following co...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Troldborg, Anne, Jensen, Lisbeth, Deleuran, Bent, Stengaard-Pedersen, Kristian, Thiel, Steffen, Jensenius, Jens Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879092/
https://ncbi.nlm.nih.gov/pubmed/29632534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00581
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