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Identification of Novel Melanin Synthesis Inhibitors From Crataegus pycnoloba Using an in Vivo Zebrafish Phenotypic Assay

Zebrafish has emerged as a powerful model organism for high throughput drug screening. Several morphological criteria, transgenic lines and in situ expression screens have been developed to identify novel bioactive compounds and their mechanism of action. Here, we used the inhibition of melanogenesi...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Front Pharmacol
Κύριοι συγγραφείς: Agalou, Adamantia, Thrapsianiotis, Michael, Angelis, Apostolis, Papakyriakou, Athanasios, Skaltsounis, Alexios-Leandros, Aligiannis, Nektarios, Beis, Dimitris
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Frontiers Media S.A. 2018
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879087/
https://ncbi.nlm.nih.gov/pubmed/29632489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00265
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