Routine Clinical Anti-Platelet Agents Have Limited Efficacy in Modulating Hypershear-Mediated Platelet Activation Associated with Mechanical Circulatory Support

INTRODUCTION: Continuous flow ventricular assist devices (cfVADs) continue to be limited by thrombotic complications associated with disruptive flow patterns and supraphysiologic shear stresses. Patients are prescribed complex antiplatelet therapies, which do not fully prevent recurrent thromboembol...

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Publicat a:Thromb Res
Autors principals: Valerio, Lorenzo, Sheriff, Jawaad, Tran, Phat L., Brengle, William, Redaelli, Alberto, Fiore, Gianfranco B., Pappalardo, Federico, Bluestein, Danny, Slepian, Marvin J.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879002/
https://ncbi.nlm.nih.gov/pubmed/29428715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2017.12.001
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