Aspirin Has Limited Ability to Modulate Shear-Mediated Platelet Activation Associated with Elevated Shear Stress of Ventricular Assist Devices

Continuous flow ventricular assist devices (cfVADs) while effective in advanced heart failure, remain plagued by thrombosis related to abnormal flows and elevated shear stress. To limit cfVAD thrombosis, patients utilize complex anti-thrombotic regimens built upon a foundation of aspirin (ASA). Whil...

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Pubblicato in:Thromb Res
Autori principali: Valerio, Lorenzo, Tran, Phat L., Sheriff, Jawaad, Brengle, William, Ghosh, Ram, Chiu, Wei-Che, Redaelli, Alberto, Fiore, Gianfranco B., Pappalardo, Federico, Bluestein, Danny, Slepian, Marvin J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924614/
https://ncbi.nlm.nih.gov/pubmed/26938158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2016.01.026
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