Aspirin Has Limited Ability to Modulate Shear-Mediated Platelet Activation Associated with Elevated Shear Stress of Ventricular Assist Devices

Continuous flow ventricular assist devices (cfVADs) while effective in advanced heart failure, remain plagued by thrombosis related to abnormal flows and elevated shear stress. To limit cfVAD thrombosis, patients utilize complex anti-thrombotic regimens built upon a foundation of aspirin (ASA). Whil...

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Bibliographic Details
Published in:Thromb Res
Main Authors: Valerio, Lorenzo, Tran, Phat L., Sheriff, Jawaad, Brengle, William, Ghosh, Ram, Chiu, Wei-Che, Redaelli, Alberto, Fiore, Gianfranco B., Pappalardo, Federico, Bluestein, Danny, Slepian, Marvin J.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924614/
https://ncbi.nlm.nih.gov/pubmed/26938158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2016.01.026
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