Routine Clinical Anti-Platelet Agents Have Limited Efficacy in Modulating Hypershear-Mediated Platelet Activation Associated with Mechanical Circulatory Support

INTRODUCTION: Continuous flow ventricular assist devices (cfVADs) continue to be limited by thrombotic complications associated with disruptive flow patterns and supraphysiologic shear stresses. Patients are prescribed complex antiplatelet therapies, which do not fully prevent recurrent thromboembol...

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Bibliografske podrobnosti
izdano v:Thromb Res
Main Authors: Valerio, Lorenzo, Sheriff, Jawaad, Tran, Phat L., Brengle, William, Redaelli, Alberto, Fiore, Gianfranco B., Pappalardo, Federico, Bluestein, Danny, Slepian, Marvin J.
Format: Artigo
Jezik:Inglês
Izdano: 2017
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879002/
https://ncbi.nlm.nih.gov/pubmed/29428715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2017.12.001
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