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Oxidized phospholipids stimulate production of stem cell factor via NRF2-dependent mechanisms

Receptor tyrosine kinase c-Kit and its ligand stem cell factor (SCF) regulate resident vascular wall cells and recruit circulating progenitors. We tested whether SCF may be induced by oxidized palmitoyl-arachidonoyl-phosphatidylcholine (OxPAPC) known to accumulate in atherosclerotic vessels. Gene ex...

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Pubblicato in:Angiogenesis
Autori principali: Afonyushkin, Taras, Oskolkova, Olga V., Bochkov, Valery N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5878191/
https://ncbi.nlm.nih.gov/pubmed/29330760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-017-9590-5
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