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Oxidized phospholipids stimulate production of stem cell factor via NRF2-dependent mechanisms

Receptor tyrosine kinase c-Kit and its ligand stem cell factor (SCF) regulate resident vascular wall cells and recruit circulating progenitors. We tested whether SCF may be induced by oxidized palmitoyl-arachidonoyl-phosphatidylcholine (OxPAPC) known to accumulate in atherosclerotic vessels. Gene ex...

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Detalhes bibliográficos
Publicado no:Angiogenesis
Main Authors: Afonyushkin, Taras, Oskolkova, Olga V., Bochkov, Valery N.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5878191/
https://ncbi.nlm.nih.gov/pubmed/29330760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-017-9590-5
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