Gasdermin D Exerts Anti-inflammatory Effects by Promoting Neutrophil Death

Gasdermin D (GSDMD) is considered a proinflammatory factor that mediates pyroptosis in macrophages to protect hosts from intracellular bacteria. Here, we reveal that GSDMD deficiency paradoxically augmented host responses to extracellular Escherichia coli, mainly by delaying neutrophil death, which...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Rep
Päätekijät: Kambara, Hiroto, Liu, Fei, Zhang, Xiaoyu, Liu, Peng, Bajrami, Besnik, Teng, Yan, Zhao, Li, Zhou, Shiyi, Yu, Hongbo, Zhou, Weidong, Silberstein, Leslie E., Cheng, Tao, Han, Mingzhe, Xu, Yuanfu, Luo, Hongbo R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5878047/
https://ncbi.nlm.nih.gov/pubmed/29539421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.02.067
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