Novel GLP-1R/GIPR co-agonist “twincretin” is neuroprotective in cell and rodent models of mild traumatic brain injury

Several single incretin receptor agonists that are approved for the treatment of type 2 diabetes mellitus (T2DM) have been shown to be neuroprotective in cell and animal models of neurodegeneration. Recently, a synthetic dual incretin receptor agonist, nicknamed “twincretin,” was shown to improve up...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: Tamargo, Ian A., Bader, Miaad, Li, Yazhou, Yu, Seong-Jin, Wang, Yun, Talbot, Konrad, DiMarchi, Richard D., Pick, Chaim G., Greig, Nigel H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5878017/
https://ncbi.nlm.nih.gov/pubmed/27845037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2016.11.005
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