Cognitive Impairments Accompanying Rodent Mild Traumatic Brain Injury Involve p53-Dependent Neuronal Cell Death and Are Ameliorated by the Tetrahydrobenzothiazole PFT-α

With parallels to concussive mild traumatic brain injury (mTBI) occurring in humans, anesthetized mice subjected to a single 30 g weight drop mTBI event to the right parietal cortex exhibited significant diffuse neuronal degeneration that was accompanied by delayed impairments in recognition and spa...

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Main Authors: Rachmany, Lital, Tweedie, David, Rubovitch, Vardit, Yu, Qian-Sheng, Li, Yazhou, Wang, Jia-Yi, Pick, Chaim G., Greig, Nigel H.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842915/
https://ncbi.nlm.nih.gov/pubmed/24312187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079837
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