Pharmacokinetics and efficacy of PT302, a sustained-release Exenatide formulation, in a murine model of mild traumatic brain injury

Traumatic brain injury (TBI) is a neurodegenerative disorder for which no effective pharmacological treatment is available. Glucagon-like peptide 1 (GLP-1) analogues such as Exenatide have previously demonstrated neuro-trophic and neuroprotective effects in cellular and animal models of TBI. However...

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Uloženo v:
Podrobná bibliografie
Vydáno v:Neurobiol Dis
Hlavní autoři: Bader, Miaad, Li, Yazhou, Lecca, Daniela, Rubovitch, Vardit, Tweedie, David, Glotfelty, Elliot, Rachmany, Lital, Kim, Hee Kyung, Choi, Ho-Il, Hoffer, Barry J., Pick, Chaim G., Greig, Nigel H., Kim, Dong Seok
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710831/
https://ncbi.nlm.nih.gov/pubmed/30471415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2018.11.023
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