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Rocaglates as dual-targeting agents for experimental cerebral malaria

Cerebral malaria (CM) is a severe and rapidly progressing complication of infection by Plasmodium parasites that is associated with high rates of mortality and morbidity. Treatment options are currently few, and intervention with artemisinin (Art) has limited efficacy, a problem that is compounded b...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Langlais, David, Cencic, Regina, Moradin, Neda, Kennedy, James M., Ayi, Kodjo, Brown, Lauren E., Crandall, Ian, Tarry, Michael J., Schmeing, Martin, Kain, Kevin C., Porco, John A., Pelletier, Jerry, Gros, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877959/
https://ncbi.nlm.nih.gov/pubmed/29463745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1713000115
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