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A comprehensive model for the proliferation–quiescence decision in response to endogenous DNA damage in human cells
Human cells that suffer mild DNA damage can enter a reversible state of growth arrest known as quiescence. This decision to temporarily exit the cell cycle is essential to prevent the propagation of mutations, and most cancer cells harbor defects in the underlying control system. Here we present a m...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5877942/ https://ncbi.nlm.nih.gov/pubmed/29463760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715345115 |
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