Visualizing the metazoan proliferation-quiescence decision in vivo

Cell proliferation and quiescence are intimately coordinated during metazoan development. Here, we adapt a cyclin-dependent kinase (CDK) sensor to uncouple these key events of the cell cycle in Caenorhabditis elegans and zebrafish through live-cell imaging. The CDK sensor consists of a fluorescently...

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Bibliographic Details
Published in:eLife
Main Authors: Adikes, Rebecca C, Kohrman, Abraham Q, Martinez, Michael A Q, Palmisano, Nicholas J, Smith, Jayson J, Medwig-Kinney, Taylor N, Min, Mingwei, Sallee, Maria D, Ahmed, Ononnah B, Kim, Nuri, Liu, Simeiyun, Morabito, Robert D, Weeks, Nicholas, Zhao, Qinyun, Zhang, Wan, Feldman, Jessica L, Barkoulas, Michalis, Pani, Ariel M, Spencer, Sabrina L, Martin, Benjamin L, Matus, David Q
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2020
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880687/
https://ncbi.nlm.nih.gov/pubmed/33350383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.63265
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