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Circular Bivalent Aptamers Enable in Vivo Stability and Recognition

Aptamers are powerful candidates for molecular imaging and targeted therapy of cancer based on such appealing features as high binding affinity, high specificity, site-specific modification and rapid tumor penetration. However, aptamers are susceptible to plasma exonucleases in vivo. This seriously...

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Bibliografiska uppgifter
I publikationen:J Am Chem Soc
Huvudupphovsmän: Kuai, Hailan, Zhao, Zilong, Mo, Liuting, Liu, Hui, Hu, Xiaoxiao, Fu, Ting, Zhang, Xiaobing, Tan, Weihong
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877791/
https://ncbi.nlm.nih.gov/pubmed/28635257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b04547
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