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Circular Bivalent Aptamers Enable in Vivo Stability and Recognition
Aptamers are powerful candidates for molecular imaging and targeted therapy of cancer based on such appealing features as high binding affinity, high specificity, site-specific modification and rapid tumor penetration. However, aptamers are susceptible to plasma exonucleases in vivo. This seriously...
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| Veröffentlicht in: | J Am Chem Soc |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5877791/ https://ncbi.nlm.nih.gov/pubmed/28635257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b04547 |
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