Molecular genetic investigation, clinical features, and response to treatment in 21 patients with Schnitzler syndrome

To date, the pathogenic mechanisms underlying Schnitzler syndrome remain obscure, in particular, the interplay between the monoclonal protein and increased interleukin-1β (IL-1β) production, although interest in the contribution of genetic factors has been fueled by detection of somatic NLRP3 mosaic...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Rowczenio, Dorota M., Pathak, Shelly, Arostegui, Juan I., Mensa-Vilaro, Anna, Omoyinmi, Ebun, Brogan, Paul, Lipsker, Dan, Scambler, Thomas, Owen, Roger, Trojer, Hadija, Baginska, Anna, Gillmore, Julian D., Wechalekar, Ashutosh D., Lane, Thirusha, Williams, Rene, Youngstein, Taryn, Hawkins, Philip N., Savic, Sinisa, Lachmann, Helen J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Immunobiology and Immunotherapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877784/
https://ncbi.nlm.nih.gov/pubmed/29284595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-10-810366
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