Molecular genetic investigation, clinical features, and response to treatment in 21 patients with Schnitzler syndrome

To date, the pathogenic mechanisms underlying Schnitzler syndrome remain obscure, in particular, the interplay between the monoclonal protein and increased interleukin-1β (IL-1β) production, although interest in the contribution of genetic factors has been fueled by detection of somatic NLRP3 mosaic...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Blood
Main Authors: Rowczenio, Dorota M., Pathak, Shelly, Arostegui, Juan I., Mensa-Vilaro, Anna, Omoyinmi, Ebun, Brogan, Paul, Lipsker, Dan, Scambler, Thomas, Owen, Roger, Trojer, Hadija, Baginska, Anna, Gillmore, Julian D., Wechalekar, Ashutosh D., Lane, Thirusha, Williams, Rene, Youngstein, Taryn, Hawkins, Philip N., Savic, Sinisa, Lachmann, Helen J.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Hematology 2018
נושאים:
Immunobiology and Immunotherapy
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877784/
https://ncbi.nlm.nih.gov/pubmed/29284595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-10-810366
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