Molecular genetic investigation, clinical features, and response to treatment in 21 patients with Schnitzler syndrome

To date, the pathogenic mechanisms underlying Schnitzler syndrome remain obscure, in particular, the interplay between the monoclonal protein and increased interleukin-1β (IL-1β) production, although interest in the contribution of genetic factors has been fueled by detection of somatic NLRP3 mosaic...

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Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Rowczenio, Dorota M., Pathak, Shelly, Arostegui, Juan I., Mensa-Vilaro, Anna, Omoyinmi, Ebun, Brogan, Paul, Lipsker, Dan, Scambler, Thomas, Owen, Roger, Trojer, Hadija, Baginska, Anna, Gillmore, Julian D., Wechalekar, Ashutosh D., Lane, Thirusha, Williams, Rene, Youngstein, Taryn, Hawkins, Philip N., Savic, Sinisa, Lachmann, Helen J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2018
Soggetti:
Immunobiology and Immunotherapy
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877784/
https://ncbi.nlm.nih.gov/pubmed/29284595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-10-810366
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