Molecular genetic investigation, clinical features, and response to treatment in 21 patients with Schnitzler syndrome

To date, the pathogenic mechanisms underlying Schnitzler syndrome remain obscure, in particular, the interplay between the monoclonal protein and increased interleukin-1β (IL-1β) production, although interest in the contribution of genetic factors has been fueled by detection of somatic NLRP3 mosaic...

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Bibliografske podrobnosti
izdano v:Blood
Main Authors: Rowczenio, Dorota M., Pathak, Shelly, Arostegui, Juan I., Mensa-Vilaro, Anna, Omoyinmi, Ebun, Brogan, Paul, Lipsker, Dan, Scambler, Thomas, Owen, Roger, Trojer, Hadija, Baginska, Anna, Gillmore, Julian D., Wechalekar, Ashutosh D., Lane, Thirusha, Williams, Rene, Youngstein, Taryn, Hawkins, Philip N., Savic, Sinisa, Lachmann, Helen J.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2018
Teme:
Immunobiology and Immunotherapy
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877784/
https://ncbi.nlm.nih.gov/pubmed/29284595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-10-810366
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