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mTORC1 and Nutrient Homeostasis: The Central Role of the Lysosome

The mechanistic target of rapamycin complex 1 (mTORC1) coordinates cellular growth and metabolism with environmental inputs to ensure that cells grow only under favourable conditions. When active, mTORC1 stimulates biosynthetic pathways including protein, lipid and nucleotide synthesis and inhibits...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Rabanal-Ruiz, Yoana, Korolchuk, Viktor I.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877679/
https://ncbi.nlm.nih.gov/pubmed/29534520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19030818
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