Impaired CD27(+)IgD(+) B Cells With Altered Gene Signature in Rheumatoid Arthritis

Natural antibodies, particularly natural IgM, are proved to play indispensable roles in the immune defenses against common infections. More recently, the protective roles of these natural IgM were also recognized in autoimmune diseases. They are mainly produced by B-1 and innate-like B cells (ILBs)....

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hu, Fanlei, Zhang, Wei, Shi, Lianjie, Liu, Xu, Jia, Yuan, Xu, Liling, Zhu, Huaqun, Li, Yingni, Xu, Dakang, Lu, Liwei, Qiu, Xiaoyan, Liu, Wanli, Qiao, Junjie, Wang, Yongfu, Li, Zhanguo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877504/
https://ncbi.nlm.nih.gov/pubmed/29628928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00626
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