Reduced CD27(−)IgD(−) B Cells in Blood and Raised CD27(−)IgD(−) B Cells in Gut-Associated Lymphoid Tissue in Inflammatory Bowel Disease

The intestinal mucosa in inflammatory bowel disease (IBD) contains increased frequencies of lymphocytes and a disproportionate increase in plasma cells secreting immunoglobulin (Ig)G relative to other isotypes compared to healthy controls. Despite consistent evidence of B lineage cells in the mucosa...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Pararasa, Chathyan, Zhang, Na, Tull, Thomas J., Chong, Ming H. A., Siu, Jacqueline H. Y., Guesdon, William, Chavele, Konstantia Maria, Sanderson, Jeremy D., Langmead, Louise, Kok, Klaartje, Spencer, Jo, Vossenkamper, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411645/
https://ncbi.nlm.nih.gov/pubmed/30891036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00361
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