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IKKα is required in the intestinal epithelial cells for tumour stemness
BACKGROUND: Colorectal cancer is a common cause of death in developed countries. Progression from adenoma to invasive carcinoma requires accumulation of mutations starting with the Adenomatous Polyposis Coli (Apc) gene. NF-κB signalling is a key element in cancer, mainly related to the activity of I...
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| 發表在: | Br J Cancer |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5877427/ https://ncbi.nlm.nih.gov/pubmed/29438366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.459 |
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