Suv4-20h1 promotes G1 to S phase transition by downregulating p21(WAF1/CIP1) expression in chronic myeloid leukemia K562 cells

Methylation of histone H4 lysine 20 (H4K20) has been associated with cancer. However, the functions of the histone methyltransferases that trigger histone H4K20 methylation in cancers, including suppressor of variegation 4–20 homolog 1 (Suv4-20h1), remain elusive. In the present study, it was demons...

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Veröffentlicht in:Oncol Lett
Hauptverfasser: Wu, Yupeng, Wang, Yadong, Liu, Ming, Nie, Min, Wang, Ying, Deng, Yexuan, Yao, Bing, Gui, Tao, Li, Xinyu, Ma, Lingling, Guo, Chan, Ma, Chi, Ju, Junyi, Zhao, Quan
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5876467/
https://ncbi.nlm.nih.gov/pubmed/29616094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8092
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