Suv4-20h1 promotes G1 to S phase transition by downregulating p21(WAF1/CIP1) expression in chronic myeloid leukemia K562 cells

Methylation of histone H4 lysine 20 (H4K20) has been associated with cancer. However, the functions of the histone methyltransferases that trigger histone H4K20 methylation in cancers, including suppressor of variegation 4–20 homolog 1 (Suv4-20h1), remain elusive. In the present study, it was demons...

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Vydáno v:Oncol Lett
Hlavní autoři: Wu, Yupeng, Wang, Yadong, Liu, Ming, Nie, Min, Wang, Ying, Deng, Yexuan, Yao, Bing, Gui, Tao, Li, Xinyu, Ma, Lingling, Guo, Chan, Ma, Chi, Ju, Junyi, Zhao, Quan
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5876467/
https://ncbi.nlm.nih.gov/pubmed/29616094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8092
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