Zeb1-Hdac2-eNOS circuitry identifies early cardiovascular precursors in naive mouse embryonic stem cells

Nitric oxide (NO) synthesis is a late event during differentiation of mouse embryonic stem cells (mESC) and occurs after release from serum and leukemia inhibitory factor (LIF). Here we show that after release from pluripotency, a subpopulation of mESC, kept in the naive state by 2i/LIF, expresses e...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Cencioni, Chiara, Spallotta, Francesco, Savoia, Matteo, Kuenne, Carsten, Guenther, Stefan, Re, Agnese, Wingert, Susanne, Rehage, Maike, Sürün, Duran, Siragusa, Mauro, Smith, Jacob G., Schnütgen, Frank, von Melchner, Harald, Rieger, Michael A., Martelli, Fabio, Riccio, Antonella, Fleming, Ingrid, Braun, Thomas, Zeiher, Andreas M., Farsetti, Antonella, Gaetano, Carlo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5876398/
https://ncbi.nlm.nih.gov/pubmed/29599503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03668-0
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