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Age-dependent increase of oxidative stress regulates microRNA-29 family preserving cardiac health
The short-lived turquoise killifish Nothobranchius furzeri (Nfu) is a valid model for aging studies. Here, we investigated its age-associated cardiac function. We observed oxidative stress accumulation and an engagement of microRNAs (miRNAs) in the aging heart. MiRNA-sequencing of 5 week (young), 12...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group UK
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5715159/ https://ncbi.nlm.nih.gov/pubmed/29203887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16829-w |
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