USP52 acts as a deubiquitinase and promotes histone chaperone ASF1A stabilization

Histone chaperone ASF1A has been reported to be dysregulated in multiple tumors; however, the underlying molecular mechanism that how the abundance and function of ASF1A are regulated remains unclear. Here we report that ASF1A is physically associated with USP52, which is previously identified as a...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Yang, Shangda, Liu, Ling, Cao, Cheng, Song, Nan, Wang, Yuejiao, Ma, Shuai, Zhang, Qi, Yu, Na, Ding, Xiang, Yang, Fuquan, Tian, Shanshan, Zhang, Kai, Sun, Tao, Yang, Jie, Yao, Zhi, Wu, Shaoyuan, Shi, Lei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5876348/
https://ncbi.nlm.nih.gov/pubmed/29599486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03588-z
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