Enterokinase Enhances Influenza A Virus Infection by Activating Trypsinogen in Human Cell Lines

Cleavage and activation of hemagglutinin (HA) by trypsin-like proteases in influenza A virus (IAV) are essential prerequisites for its successful infection and spread. In host cells, some transmembrane serine proteases such as TMPRSS2, TMPRSS4 and HAT, along with plasmin in the bloodstream, have bee...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Hayashi, Hideki, Kubo, Yoshinao, Izumida, Mai, Takahashi, Etsuhisa, Kido, Hiroshi, Sato, Ko, Yamaya, Mutsuo, Nishimura, Hidekazu, Nakayama, Kou, Matsuyama, Toshifumi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5876233/
https://ncbi.nlm.nih.gov/pubmed/29629340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2018.00091
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