Enterokinase Enhances Influenza A Virus Infection by Activating Trypsinogen in Human Cell Lines

Cleavage and activation of hemagglutinin (HA) by trypsin-like proteases in influenza A virus (IAV) are essential prerequisites for its successful infection and spread. In host cells, some transmembrane serine proteases such as TMPRSS2, TMPRSS4 and HAT, along with plasmin in the bloodstream, have bee...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Cell Infect Microbiol
Hauptverfasser: Hayashi, Hideki, Kubo, Yoshinao, Izumida, Mai, Takahashi, Etsuhisa, Kido, Hiroshi, Sato, Ko, Yamaya, Mutsuo, Nishimura, Hidekazu, Nakayama, Kou, Matsuyama, Toshifumi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5876233/
https://ncbi.nlm.nih.gov/pubmed/29629340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2018.00091
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