Enterokinase Enhances Influenza A Virus Infection by Activating Trypsinogen in Human Cell Lines

Cleavage and activation of hemagglutinin (HA) by trypsin-like proteases in influenza A virus (IAV) are essential prerequisites for its successful infection and spread. In host cells, some transmembrane serine proteases such as TMPRSS2, TMPRSS4 and HAT, along with plasmin in the bloodstream, have bee...

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Dades bibliogràfiques
Publicat a:Front Cell Infect Microbiol
Autors principals: Hayashi, Hideki, Kubo, Yoshinao, Izumida, Mai, Takahashi, Etsuhisa, Kido, Hiroshi, Sato, Ko, Yamaya, Mutsuo, Nishimura, Hidekazu, Nakayama, Kou, Matsuyama, Toshifumi
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5876233/
https://ncbi.nlm.nih.gov/pubmed/29629340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2018.00091
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