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Targeted adenovirus-induced expression of IL-10 decreases thymic apoptosis and improves survival in murine sepsis
Sepsis remains a significant clinical conundrum, and recent clinical trials with anticytokine therapies have produced disappointing results. Animal studies have suggested that increased lymphocyte apoptosis may contribute to sepsis-induced mortality. We report here that inhibition of thymocyte apopt...
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| Main Authors: | , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The National Academy of Sciences
2001
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC58759/ https://ncbi.nlm.nih.gov/pubmed/11553765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181338198 |
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