Extended lung expression and increased tissue localization of viral IL-10 with adenoviral gene therapy

IL-10 is a pleiotropic cytokine that acts as an important regulator of macrophage, T cell, and natural killer cell functions. Human IL-10 (hIL-10) has both stimulatory and inhibitory effects on a wide variety of cell types. Viral IL-10 (vIL-10) possesses only a subset of hIL-10's activities, pr...

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Detalhes bibliográficos
Main Authors: Minter, Rebecca M., Ferry, Maria A., Rectenwald, John E., Bahjat, F. R., Oberholzer, Andreas, Oberholzer, Caroline, La Face, Drake, Tsai, Van, Ahmed, C. M. Iqbal, Hutchins, Beth, Copeland, Edward M., Ginsberg, Harold S., Moldawer, Lyle L.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC14581/
https://ncbi.nlm.nih.gov/pubmed/11134537
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