Á lódáil...
Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase
Oxygen radicals, which can be produced through normal cellular metabolism, are thought to play an important role in mutagenesis and tumorigenesis. Among various classes of oxidative DNA damage, 8-oxo-7,8-dihydroguanine (8-oxoG) is most important because of its abundance and mutagenicity. The MTH1 ge...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
The National Academy of Sciences
2001
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC58751/ https://ncbi.nlm.nih.gov/pubmed/11572992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191086798 |
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