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Discovery of physiological and cancer-related regulators of 3′ UTR processing with KAPAC

3′ Untranslated regions (3' UTRs) length is regulated in relation to cellular state. To uncover key regulators of poly(A) site use in specific conditions, we have developed PAQR, a method for quantifying poly(A) site use from RNA sequencing data and KAPAC, an approach that infers activities of...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Gruber, Andreas J., Schmidt, Ralf, Ghosh, Souvik, Martin, Georges, Gruber, Andreas R., van Nimwegen, Erik, Zavolan, Mihaela
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875010/
https://ncbi.nlm.nih.gov/pubmed/29592812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1415-3
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