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Discovery of physiological and cancer-related regulators of 3′ UTR processing with KAPAC

3′ Untranslated regions (3' UTRs) length is regulated in relation to cellular state. To uncover key regulators of poly(A) site use in specific conditions, we have developed PAQR, a method for quantifying poly(A) site use from RNA sequencing data and KAPAC, an approach that infers activities of...

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Vydáno v:Genome Biol
Hlavní autoři: Gruber, Andreas J., Schmidt, Ralf, Ghosh, Souvik, Martin, Georges, Gruber, Andreas R., van Nimwegen, Erik, Zavolan, Mihaela
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875010/
https://ncbi.nlm.nih.gov/pubmed/29592812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1415-3
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