Uninfected Bystander Cells Impact the Measurement of HIV-Specific Antibody-Dependent Cellular Cytotoxicity Responses

The conformation of the HIV-1 envelope glycoprotein (Env) substantially impacts antibody recognition and antibody-dependent cellular cytotoxicity (ADCC) responses. In the absence of the CD4 receptor at the cell surface, primary Envs sample a “closed” conformation that occludes CD4-induced (CD4i) epi...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Richard, Jonathan, Prévost, Jérémie, Baxter, Amy E., von Bredow, Benjamin, Ding, Shilei, Medjahed, Halima, Delgado, Gloria G., Brassard, Nathalie, Stürzel, Christina M., Kirchhoff, Frank, Hahn, Beatrice H., Parsons, Matthew S., Kaufmann, Daniel E., Evans, David T., Finzi, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874913/
https://ncbi.nlm.nih.gov/pubmed/29559570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00358-18
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